Source: | Mouse | Gene Id: | 332 |
Isotype: | IgG1 | Swiss Prot: | O15392 |
purity: | Affinity chromatography |
Background: |
survivin is an apoptosis inhibitor that is expressed during the G2/M phase of the cell cycle. Associates with the microtubules of the mitotic spindle and any disruption results in the loss of apoptosis activity. May play a role in neoplasia. Inhibitor of caspase-3 and caspase-7. Two splice variant isoforms have been described. |
Reactivity | Human |
Tested applications | WB IHC ELISA ICC FC |
Clonality | Monoclonal Antibody |
Calculated MW | 16 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human BIRC5 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | API4, Apoptosis inhibitor 4, Apoptosis inhibitor survivin, BIRC5, Baculoviral IAP repeat-containing protein 5, IAP4, TIAP |
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