Source: | Mouse | Gene Id: | 79727 |
Isotype: | IgG1 | Swiss Prot: | Q9H9Z2 |
purity: | Affinity chromatography |
Background: |
LIN28: lin-28 homolog (C. elegans), also known as CSDD1, ZCCHC1. Entrez Protein NP_078950. LIN28 was first discovered in the nematode C. elegans. It is a heterochronic protein in C. elegans involved in the timing of developmental events and choice of stage specific cell fates. LIN28 expression has been found to be regulated post-transcriptionally by miRNAs in both nematodes and mammals. In humans it is expressed in embryonic stem cells and its expression decreases during differentiation. It is negatively regulated by retinoic acid in neuronal differentiation. |
Reactivity | Human |
Tested applications | WB ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 23 kDa |
Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human LIN28 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CSDD1, LIN-28, LIN28A, ZCCHC1 |
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