Source: | Mouse | Gene Id: | 4145 |
Isotype: | IgG1 | Swiss Prot: | P42679 |
purity: | Affinity chromatography |
Background: |
MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. |
Reactivity | Human |
Tested applications | WB ELISA FC |
Clonality | Monoclonal Antibody |
Calculated MW | 56 kDa |
Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human MATK expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CHK, CTK |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.