CTTN Mouse Monoclonal Antibody
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AMM2017-61 50ul 1500.00 In Stock
AMM2017-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 2017
Isotype: IgG1 Swiss Prot: Q14247
purity: Affinity chromatography
Background:
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. (provided by RefSeq)
Reactivity Human, Mouse
Tested applications WB IHC ELISA
Clonality Monoclonal Antibody
Calculated MW 80 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:200-1:1000
Immunogen A purified recombinant fragment of human CTTN expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym EMS1, FLJ34459, CTTN
This product is for research use only, not for diagnostic or therapeutic use!

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