Source: | Mouse | Gene Id: | 3856 |
Isotype: | IgG1 | Swiss Prot: | P05787 |
purity: | Affinity chromatography |
Background: |
Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP_002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. |
Reactivity | Human |
Tested applications | WB IHC ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 54 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human Cytokeratin 8 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CK8, CYK8, K2C8, KRT8 |
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