Source: | Mouse | Gene Id: | 925 |
Isotype: | IgG1 | Swiss Prot: | P01732 |
purity: | Affinity chromatography |
Background: |
CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds .It belongs type I membrane protein. Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development. Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing. Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine- protein kinase p56lck. |
Reactivity | Human |
Tested applications | ELISA FC |
Clonality | Monoclonal Antibody |
Calculated MW | 25 kDa |
Recommended Dilutions |
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human CD8 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CD8, MAL, p32, Leu2, CD8A |
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