Source: | Mouse | Gene Id: | 4318 |
Isotype: | IgG1 | Swiss Prot: | P14780 |
purity: | Affinity chromatography |
Background: |
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. |
Reactivity | Human |
Tested applications | WB IHC ELISA ICC FC |
Clonality | Monoclonal Antibody |
Calculated MW | 92 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human MMP9 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EC 3.4.24.35MMP992 kDa type IV collagenase92 kDa gelatinaseGelatinase BGELB |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.