Source: | Mouse | Gene Id: | 3815 |
Isotype: | IgG1 | Swiss Prot: | P10721 |
purity: | Affinity chromatography |
Background: |
C-kit (CD117, 145kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 145 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human C-Kit expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | PBT, SCFR, C-Kit, CD117, KIT |
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