ROR1 Mouse Monoclonal Antibody
No Size Price Availability  
AMM4919-61 50ul 1500.00 In Stock
AMM4919-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 4919
Isotype: IgG1 Swiss Prot: Q01973
purity: Affinity chromatography
Background:
ROR1, a type I membrane protein, is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases.
Reactivity Human
Tested applications WB ELISA ICC
Clonality Monoclonal Antibody
Calculated MW 101 kDa
Recommended Dilutions
WB 1:500-1:2000
FC 1:200-1:400
Immunogen A purified recombinant fragment of human ROR1 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym ROR1
This product is for research use only, not for diagnostic or therapeutic use!

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