Source: | Mouse | Gene Id: | 929 |
Isotype: | IgG1 | Swiss Prot: | P08571 |
purity: | Affinity chromatography |
Background: |
CD14 antigen is a GPI-linked glycoprotein with a molecular weight of 55kD. The CD14 antigen is expressed on cells of the myelomonocytic lineage including monocytes, macrophages and Langerhans cells. Low expression is observed on neutrophils and on human B cells. CD14 antigen is a receptor for bacterial lipopolysaccharide (LPS, endotoxin) and the lipopolysaccharide binding protein (LBP). LBP and CD14 antigen serves two physiological roles. These proteins act as opsonin and opsonic receptor, respectively, to promote the phagocytic uptake of bacteria or LPScoated particles by macrophages. |
Reactivity | Human |
Tested applications | IHC ELISA FC |
Clonality | Monoclonal Antibody |
Calculated MW | 40 kDa |
Recommended Dilutions |
IHC 1:200-1:1000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human CD14 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CD14 |
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