Source: | Mouse | Gene Id: | 3055 |
Isotype: | IgG1 | Swiss Prot: | P08631 |
purity: | Affinity chromatography |
Background: |
The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization. |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 59 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human HCK expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | B-cell/myeloid kinase, BMK, EC 2.7.10.2, Hemopoietic cell kinase, P56-HCK and P60-HCK, Tyrosine-protein kinase HCK, kinase Hck, p59-HCK/p60-HCK |
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