| No | Size | Price | Availability | |
| AMM9451-61 | 50ul | 1500.00 | In Stock |  |
| AMM9451-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 9451 |
| Isotype: | IgG1 | Swiss Prot: | Q9NZJ5 |
| purity: | Affinity chromatography |
| Background: |
| The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 125 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A purified recombinant fragment of human EIF2AK3 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | EC 2.7.11.1PRKR-like endoplasmic reticulum kinasePancreatic eIF2-alpha kinaseHsPEK |
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