Source: | Mouse | Gene Id: | 8842 |
Isotype: | IgG1 | Swiss Prot: | O43490 |
purity: | Affinity chromatography |
Background: |
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. |
Reactivity | Human |
Tested applications | IHC ELISA FC ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 133 kDa |
Recommended Dilutions |
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human CD133 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | RP41, AC133, CD133, MCDR2, STGD4, CORD12, PROML1, MSTP061 |
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