Source: | Mouse | Gene Id: | 4916 |
Isotype: | IgG1 | Swiss Prot: | Q16288 |
purity: | Affinity chromatography |
Background: |
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 94 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A purified recombinant fragment of human NTRK3 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EC 2.7.10.1Neurotrophic tyrosine kinase receptor type 3TrkC tyrosine kinaseGP145-TrkCTrk-C |
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