Source: | Mouse | Gene Id: | 367 |
Isotype: | IgG1 | Swiss Prot: | P10275 |
purity: | Affinity chromatography |
Background: |
The androgen receptor (AR), also known as NR3C4 (nuclear receptor subfamily 3, group C, member 4), is a type of nuclear receptor which is activated by binding of either of the androgenic hormones testosterone or dihydrotestosterone in the cytoplasm and then translocating into the nucleus. The androgen receptor is most closely related to the progesterone receptor, and progestins in higher dosages can block the androgen receptor. The main function of the androgen receptor is as a DNA binding transcription factor which regulates gene expression; however, the androgen receptor has other functions as well. Androgen regulated genes are critical for the development and maintenance of the male sexual phenotype. |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 110 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human Androgen receptor expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | NR3C4, KD, AIS, SMAX1, HUMARA, AR |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.