BMPR2 Mouse Monoclonal Antibody
No Size Price Availability  
AMM659-61 50ul 1500.00 In Stock
AMM659-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 659
Isotype: IgG1 Swiss Prot: Q13873
purity: Affinity chromatography
Background:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. (provided by RefSeq)
Reactivity Human, Monkey, Mouse, Rat
Tested applications WB IHC ELISA
Clonality Monoclonal Antibody
Calculated MW 115 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:200-1:1000
Immunogen A purified recombinant fragment of human BMPR2 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym BMR2, PPH1, BMPR3, BRK-3, T-ALK, BMPR-II, FLJ41585, FLJ76945, BMPR2
This product is for research use only, not for diagnostic or therapeutic use!

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