Source: | Mouse | Gene Id: | 5600 |
Isotype: | IgG1 | Swiss Prot: | Q15759 |
purity: | Affinity chromatography |
Background: |
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. Alternatively spliced transcript variants encoding the same protein have been observed. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 42 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A purified recombinant fragment of human MAPK11 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EC 2.7.1.37, EC 2.7.11.24, MAP kinase p38 beta, MAPK11, mitogen-activated protein kinase 11, mitogen-activated protein kinase p38 beta, MK11, p38-2, p38b, PRKM11, SAPK2, stress-activated protein kinase-2 |
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