Source: | Mouse | Gene Id: | 4524 |
Isotype: | IgG1 | Swiss Prot: | P42898 |
purity: | Affinity chromatography |
Background: |
The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. |
Reactivity | Human, Rat |
Tested applications | WB IHC ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 75 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human MTHFR expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | MTHFR |
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