Source: | Mouse | Gene Id: | 4436 |
Isotype: | IgG1 | Swiss Prot: | P43246 |
purity: | Affinity chromatography |
Background: |
MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. |
Reactivity | Human, Monkey |
Tested applications | WB IHC ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 105 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human MSH2 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | COCA1, DNA mismatch repair protein Msh2, FCC1, HNPCC, HNPCC1, MutS protein homolog 2, mutS (E. coli) homolog 2 |
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