Source: | Mouse | Gene Id: | 4026 |
Isotype: | IgG1 | Swiss Prot: | Q93052 |
purity: | Affinity chromatography |
Background: |
LIM domain containing preferred translocation partner in lipoma. The Zyxin family of proteins contains five members, Ajuba, LIMD1, LPP,TRIP6 and Zyxin. LPP (LIM-containing lipoma-preferred partner), a LIM domain-containing scaffolding protein contains three LIM domains at its carboxy terminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. LPP, an 80 kDa protein, localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts,and shuttles to the nucleus where it has transcriptional activation capacity.The human LPP gene maps to chromosomal location 3q28, and preferentially translocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas. |
Reactivity | Hamster, Human, Monkey, Mouse |
Tested applications | WB IHC ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 66 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human LPP expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | LPP |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved.