| No | Size | Price | Availability | |
| AMM3099-61 | 50ul | 1500.00 | In Stock |  |
| AMM3099-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 3099 |
| Isotype: | IgG1 | Swiss Prot: | P52789 |
| purity: | Affinity chromatography |
| Background: |
| Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3). |
| Reactivity | Human |
| Tested applications | WB IHC ELISA FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 102 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human HK2 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | HK2, DKFZp686M1669, HKII, HXK2 |
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