| No | Size | Price | Availability | |
| AMM1977-61 | 50ul | 1500.00 | In Stock |  |
| AMM1977-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 1977 |
| Isotype: | IgG1 | Swiss Prot: | P06730 |
| purity: | Affinity chromatography |
| Background: |
| eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types. Several kinases are currently being investigated as potential regulators of eIF4E including PKC and/or the MAP kinase activated Mnk. |
| Reactivity | Human |
| Tested applications | WB IHC ELISA ICC FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 25 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human EIF4E expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CBP, EIF4F, EIF4E1, EIF4EL1, MGC111573, EIF4E |
沪ICP备15003525号 Copyright ©, 2013-2019, Yihyson All Rights Reserved. 
