| No | Size | Price | Availability | |
| AMM1759-61 | 50ul | 1500.00 | In Stock |  |
| AMM1759-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 1759 |
| Isotype: | IgG1 | Swiss Prot: | Q05193 |
| purity: | Affinity chromatography |
| Background: |
| Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation. |
| Reactivity | Human |
| Tested applications | WB IHC ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 97 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
|
| Immunogen | A purified recombinant fragment of human Dynamin-1 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DNM, DNM1 |
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