Source: | Mouse | Gene Id: | 27 |
Isotype: | IgG1 | Swiss Prot: | P42684 |
purity: | Affinity chromatography |
Background: |
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. |
Reactivity | Human, Mouse |
Tested applications | WB ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 128 kDa |
Recommended Dilutions |
WB 1:500-1:2000
ICC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human ABL2 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | ARG, ABLL |
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