| No | Size | Price | Availability | |
| AMM6310-61 | 50ul | 1500.00 | In Stock |  |
| AMM6310-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 6310 |
| Isotype: | IgG1 | Swiss Prot: | P54253 |
| purity: | Affinity chromatography |
| Background: |
| ataxin-1 is a spinocerebellar ataxia type 1 (SCA1) protein. Expansion of CAG repeats in the SCA1 gene results in an abnormally long polyglutamine tract in the protein, causing polyglutamine-induced neurodegeneration. 14-3-3 and Akt kinase stabilize both wild-type and mutant forms of ataxin-1. The expansion of the polyglutamine tract may alter this function. |
| Reactivity | Human |
| Tested applications | WB IHC ELISA ICC FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 87 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human ATXN1 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ATX1, ATXN1, SCA1, Spinocerebellar ataxia type 1 protein, Spinocerebellar ataxia type 1 protein homolog |
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