GSTM1 Mouse Monoclonal Antibody
No Size Price Availability  
AMM2944-61 50ul 1500.00 In Stock
AMM2944-61 100ul 2000.00 In Stock
  • Details
  • FAQs
  • Manual
Source: Mouse Gene Id: 2944
Isotype: IgG1 Swiss Prot: P09488
purity: Affinity chromatography
Background:
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.
Reactivity Human, Rat
Tested applications WB IHC ELISA FC
Clonality Monoclonal Antibody
Calculated MW 26 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:200-1:1000
FC 1:200-1:400
Immunogen A purified recombinant fragment of human GSTM1 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym MU, H-B, GST1, GTH4, GTM1, MU-1, GSTM1-1, MGC26563, GSTM1a-1a, GSTM1b-1b
This product is for research use only, not for diagnostic or therapeutic use!

backtop
QQ
service center
Contact Us