Source: | Mouse | Gene Id: | 5468 |
Isotype: | IgG1 | Swiss Prot: | P37231 |
purity: | Affinity chromatography |
Background: |
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. |
Reactivity | Human |
Tested applications | WB ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 58 kDa |
Recommended Dilutions |
WB 1:500-1:2000
|
Immunogen | A purified recombinant fragment of human PPARG expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma |
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