| No | Size | Price | Availability | |
| AMM3689-61 | 50ul | 1500.00 | In Stock |  |
| AMM3689-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 3689 |
| Isotype: | IgG1 | Swiss Prot: | P05107 |
| purity: | Affinity chromatography |
| Background: |
| CD18, also known as ITGB2 (integrin beta chain beta 2). Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. CD18 is expressed by most leucocytes. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. |
| Reactivity | Human, Mouse |
| Tested applications | ELISA ICC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 85 kDa |
| Recommended Dilutions |
ICC 1:200-1:1000
|
| Immunogen | A purified recombinant fragment of human CD18 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | LAD, MF17, LCAMB, LFA-1, ITGB2 |
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