PSIP1 Mouse Monoclonal Antibody
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AMM11168-61 50ul 1500.00 In Stock
AMM11168-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 11168
Isotype: IgG1 Swiss Prot: O75475
purity: Affinity chromatography
Background:
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.
Reactivity Human, Monkey, Rat
Tested applications WB IHC ELISA ICC
Clonality Monoclonal Antibody
Calculated MW 75 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
Immunogen A purified recombinant fragment of human PSIP1 expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym p52, p75, PAIP, DFS70, LEDGF, PSIP2, MGC74712, PSIP1
This product is for research use only, not for diagnostic or therapeutic use!

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