| No | Size | Price | Availability | |
| AMM5586-61 | 50ul | 1500.00 | In Stock |  |
| AMM5586-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 5586 |
| Isotype: | IgG1 | Swiss Prot: | Q16513 |
| purity: | Affinity chromatography |
| Background: |
| Protein-kinase-C-related kinases (PRKs) are part of the lipid-regulated protein kinases (PKC) which also include liver PAK & PKN. Human PRK1 and PRK2 share structurally similar catalytic domains, but less similar N-terminal regulatory regions suggesting different regulatory domain functions. PRK1 and PRK2, as well as a third member of this family, PRK3, show distinct patterns of expression in adult tissues. Additionally, the serine-threonine kinase PRK2 can be specifically cleaved by caspase-3 (and/or caspase-3-like subfamily members) during apoptosis. |
| Reactivity | Human, Monkey, Mouse, Rat |
| Tested applications | WB IHC ELISA FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 140 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human PRK2 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | PKN2, PAK2, PRK2, Pak-2, PRKCL2, PRO2042, MGC71074, MGC150606 |
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