| No | Size | Price | Availability | |
| AMM3586-61 | 50ul | 1500.00 | In Stock |  |
| AMM3586-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 3586 |
| Isotype: | IgG1 | Swiss Prot: | P22301 |
| purity: | Affinity chromatography |
| Background: |
| Interleukine 10 (IL-10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down- regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 21 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A purified recombinant fragment of human IL-10 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | IL10 |
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