INHA (Inhibin alpha) Mouse Monoclonal Antibody
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AMM3623-61 50ul 1500.00 In Stock
AMM3623-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 3623
Isotype: IgG1 Swiss Prot: P05111
purity: Affinity chromatography
Background:
INHA (A-inhibin subunit precursor, inhibin alpha subunit ), also called inhibin (alpha) ,which is located on chromosome 2q33-q36. Inhibin is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises of two subunits,Inhibin A and B. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa cell tumors and can therefore be used as a marker for primary as well as recurrent disease. In addition to their role in endocrine feedback in the reproductive sytem, inhibins subserve local regulatory roles in numerous extragonadal tissues, including brain, adrenal,bone marrow, placenta, and most notably anterior pituitary. Inhibin alpha subunit gene expression is down regulated in human prostate cancer, suggesting a tumor suppressive role.
Reactivity Human
Tested applications IHC ELISA ICC
Clonality Monoclonal Antibody
Calculated MW 40 kDa
Recommended Dilutions
IHC 1:200-1:1000
ICC 1:200-1:1000
Immunogen A purified recombinant fragment of human INHA (Inhibin alpha) expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym INHA, inhibin, alpha
This product is for research use only, not for diagnostic or therapeutic use!

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