| No | Size | Price | Availability | |
| AMM5657-61 | 50ul | 1500.00 | In Stock |  |
| AMM5657-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 5657 |
| Isotype: | IgG1 | Swiss Prot: | P24158 |
| purity: | Affinity chromatography |
| Background: |
| Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis. |
| Reactivity | Human |
| Tested applications | WB ELISA |
| Clonality | Monoclonal Antibody |
| Calculated MW | 28 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
|
| Immunogen | A purified recombinant fragment of human Proteinase 3 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | PRTN3, ACPA, CANCA |
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