C-CBL Mouse Monoclonal Antibody
No Size Price Availability  
AMM867-61 50ul 1500.00 In Stock
AMM867-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 867
Isotype: IgG1 Swiss Prot: P22681
purity: Affinity chromatography
Background:
The cbl oncogene was first identified as part of a transforming retrovirus which induces mouse pre-B and pro-B cell lymphomas. As an adaptor protein for receptor protein-tyrosine kinases, it positively regulates receptor protein-tyrosine kinase ubiquitination in a manner dependent upon its variant SH2 and RING finger domains. Ubiquitination of receptor protein-tyrosine kinases terminates signaling by marking active receptors for degradation.
Reactivity Human, Mouse, Rat
Tested applications WB IHC ELISA ICC FC
Clonality Monoclonal Antibody
Calculated MW 120 kDa
Recommended Dilutions
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
Immunogen A purified recombinant fragment of human C-CBL expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym CBL, CBL2, NSLL, C-CBL, RNF55
This product is for research use only, not for diagnostic or therapeutic use!

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