Source: | Mouse | Gene Id: | 2242 |
Isotype: | IgG1 | Swiss Prot: | P07332 |
purity: | Affinity chromatography |
Background: |
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified. |
Reactivity | Human |
Tested applications | WB IHC ELISA |
Clonality | Monoclonal Antibody |
Calculated MW | 93 kDa. |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
|
Immunogen | A purified recombinant fragment of human FES expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | C-FES, EC 2.7.10.2, FES/FPS, FPS, kinase Fes |
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