Source: | Mouse | Gene Id: | 4171 |
Isotype: | IgG1 | Swiss Prot: | P49736 |
purity: | Affinity chromatography |
Background: |
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7. |
Reactivity | Human, Monkey, Mouse, Rat |
Tested applications | WB IHC ELISA FC |
Clonality | Monoclonal Antibody |
Calculated MW | 125 kDa |
Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human MCM2 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | BM28, CCNL1, CDCL1, cdc19, D3S3194, MITOTIN, KIAA0030, MGC10606 |
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