| No | Size | Price | Availability | |
| AMM25898-61 | 50ul | 1500.00 | In Stock |  |
| AMM25898-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 25898 |
| Isotype: | IgG1 | Swiss Prot: | Q96PM5 |
| purity: | Affinity chromatography |
| Background: |
| Pirh 2 (P53 induced RING-H2 protein), also known as RCHY1, it forms dimers through its N- and C-terminus in cells. The Pirh2 has ubiquitin-protein ligase activity and it binds with p53 and promotes the ubiquitin-mediated proteosomal degradation of p53. The Pirh2 is oncogenic because loss of p53 function contributes directly to malignant tumor development. |
| Reactivity | Human, Rat |
| Tested applications | WB IHC ELISA ICC FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 30,60 kDa(homodimer) |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human Pirh2 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | ARNIP, CHIMP, RNF199, RCHY1 |
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