
| Source: | Mouse | Gene Id: | 1399 |
| Isotype: | IgG1 | Swiss Prot: | P46109 |
| purity: | Affinity chromatography |
| Background: |
| This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. |
| Reactivity | Human |
| Tested applications | WB ELISA FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 39 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human CRKL expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | CRKL |
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