Source: | Mouse | Gene Id: | 1399 |
Isotype: | IgG1 | Swiss Prot: | P46109 |
purity: | Affinity chromatography |
Background: |
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic. |
Reactivity | Human |
Tested applications | WB ELISA FC |
Clonality | Monoclonal Antibody |
Calculated MW | 39 kDa |
Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human CRKL expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | CRKL |
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