| No | Size | Price | Availability | |
| AMM4292-61 | 50ul | 1500.00 | In Stock |  |
| AMM4292-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 4292 |
| Isotype: | IgG1 | Swiss Prot: | P40692 |
| purity: | Affinity chromatography |
| Background: |
| This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. |
| Reactivity | Human, Monkey |
| Tested applications | WB IHC ELISA ICC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 85 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
|
| Immunogen | A purified recombinant fragment of human MLH1 expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | DNA mismatch repair protein Mlh1, MutL protein homolog 1, COCA2 |
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