Source: | Mouse | Gene Id: | 2050 |
Isotype: | IgG1 | Swiss Prot: | P54760 |
purity: | Affinity chromatography |
Background: |
Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. |
Reactivity | Human |
Tested applications | WB ELISA ICC |
Clonality | Monoclonal Antibody |
Calculated MW | 108 kDa |
Recommended Dilutions |
WB 1:500-1:2000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human EPHB4 expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | EC 2.7.1.112, EC 2.7.10.1, EPB4, Ephrin type-B receptor 4 precursor, HTK, Tyrosine-protein kinase receptor HTK |
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