Source: | Mouse | Gene Id: | 3987 |
Isotype: | IgG1 | Swiss Prot: | P48059 |
purity: | Affinity chromatography |
Background: |
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. |
Reactivity | Human |
Tested applications | WB ELISA ICC FC |
Clonality | Monoclonal Antibody |
Calculated MW | 37 kDa |
Recommended Dilutions |
WB 1:500-1:2000
ICC 1:200-1:1000
FC 1:200-1:400
|
Immunogen | A purified recombinant fragment of human PINCH expressed in E. Coli |
Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
Synonym | PINCH, PINCH1, PINCH-1, LIMS1 |
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