PINCH Mouse Monoclonal Antibody
No Size Price Availability  
AMM3987-61 50ul 1500.00 In Stock
AMM3987-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 3987
Isotype: IgG1 Swiss Prot: P48059
purity: Affinity chromatography
Background:
The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading.
Reactivity Human
Tested applications WB ELISA ICC FC
Clonality Monoclonal Antibody
Calculated MW 37 kDa
Recommended Dilutions
WB 1:500-1:2000
ICC 1:200-1:1000
FC 1:200-1:400
Immunogen A purified recombinant fragment of human PINCH expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym PINCH, PINCH1, PINCH-1, LIMS1
This product is for research use only, not for diagnostic or therapeutic use!

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