ACLY Mouse Monoclonal Antibody
No Size Price Availability  
AMM47-61 50ul 1500.00 In Stock
AMM47-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 47
Isotype: IgG1 Swiss Prot: P53396
purity: Affinity chromatography
Background:
ACLY(ATP-citrate synthase) is also named as ACL. It is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA. ACLY serves as not only a target in oxygenated cells for suppression of lipid synthesis and histone acetylation, but also as a susceptible target in hypoxic cells to restore inhibition of glycolysis. In nonsmall cell lung carcinoma and hepatocellular carcinoma ,ACLY is overexpressed compared with normal parenchyma suggesting that ACLY may represent a common target among highly malignant tumors(PMID:19795461). This protein has 2 isoforms produced by alternative splicing. This antibody is specific to ACLY.
Reactivity Human, Monkey, Mouse
Tested applications WB IHC ELISA ICC FC
Clonality Monoclonal Antibody
Calculated MW 125 kDa
Recommended Dilutions
WB 1:500-1:1000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
Immunogen A purified recombinant fragment of human ACLY expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym ACL, ATPCL, CLATP
This product is for research use only, not for diagnostic or therapeutic use!

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