SFTPC Mouse Monoclonal Antibody
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AMM6440-61 50ul 1500.00 In Stock
AMM6440-61 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 6440
Isotype: IgG1 Swiss Prot: P11686
purity: Affinity chromatography
Background:
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults.
Reactivity Human
Tested applications WB ELISA
Clonality Monoclonal Antibody
Calculated MW 21 kDa
Recommended Dilutions
WB 1:500-1:2000
Immunogen A purified recombinant fragment of human SFTPC expressed in E. Coli
Storage Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles.
Synonym SP-C, PSP-C, SFTP2, SMDP2
This product is for research use only, not for diagnostic or therapeutic use!

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