| No | Size | Price | Availability | |
| AMM5660-61 | 50ul | 1500.00 | In Stock |  |
| AMM5660-61 | 100ul | 2000.00 | In Stock | |
| Source: | Mouse | Gene Id: | 5660 |
| Isotype: | IgG1 | Swiss Prot: | P07602 |
| purity: | Affinity chromatography |
| Background: |
| This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Reactivity | Human |
| Tested applications | WB IHC ELISA ICC FC |
| Clonality | Monoclonal Antibody |
| Calculated MW | 58 kDa |
| Recommended Dilutions |
WB 1:500-1:2000
IHC 1:200-1:1000
ICC 1:200-1:1000
FC 1:200-1:400
|
| Immunogen | A purified recombinant fragment of human PSAP expressed in E. Coli |
| Storage | Store at -20°C or -80°C in PBS with 0.02% sodium azide and 50% glycerol. Avoid freeze/thaw cycles. |
| Synonym | GLBA, SAP1 |
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