CRP (C11F2) Mouse Monoclonal Antibody
No Size Price Availability  
YMM00396-01 50ul 1500.00 In Stock
YMM00396-01 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 1401
Isotype: IgG Swiss Prot:
purity: Purified by Protein G.
Background:
C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.
Reactivity Human
Tested applications WB IHC IF
Clonality Monoclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen Recombinant CRP protein
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym C reactive protein pentraxin related, CRP, MGC88244, PTX 1, PTX1, C Reactive Protein.
This product is for research use only, not for diagnostic or therapeutic use!

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