beta-Amyloid (1-42) (1F4) Mouse Monoclonal Antibody
No Size Price Availability  
YMM00112-01 50ul 1500.00 In Stock
YMM00112-01 100ul 2000.00 In Stock
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Source: Mouse Gene Id: 351
Isotype: IgG Swiss Prot:
purity: Purified by Protein G.
Background:
The cerebral and vascular plaques associated with Alzheimer's disease are mainly composed of Amyloid beta peptides. beta Amyloid is derived from cleavage of the Amyloid precursor protein and varies in length from 39 to 43 amino acids. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides result from cleavage of Amyloid precursor protein after residues 40, 42, and 43, respectively. The cleavage takes place by gamma-secretase during the last Amyloid precursor protein processing step. beta Amyloid [1-40], beta Amyloid [1-42], and beta Amyloid [1-43] peptides are major constituents of the plaques and tangles that occur in Alzheimer's disease. beta Amyloid and peptides have been developed as tools for elucidating the biology of Alzheimer's disease.
Reactivity Human, Rat
Tested applications WB IHC IF
Clonality Monoclonal Antibody
Calculated MW /
Recommended Dilutions
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
Immunogen KLH conjugated synthetic peptide derived from human beta-Amyloid (1-42)
Storage Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
Synonym
This product is for research use only, not for diagnostic or therapeutic use!

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