| No | Size | Price | Availability | |
| YRP00921-01 | 50ul | 1500.00 | In Stock |  |
| YRP00921-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 22242 |
| Isotype: | IgG | Swiss Prot: | Q91X17 |
| purity: | Purified by Protein A. |
| Background: |
| Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure providing the water barrier permeability. May serve as a receptor for binding and endocytosis for cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelial (By similarity). Uromodulin, secreted form: Secreted into urine after proteolytically cleaveage. Into the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and modulates formation of supersaturated salts and their crystals. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from mouse MCKD2 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | THP, Urehd1, urehr4, Uromodulin, Tamm-Horsfall urinary glycoprotein, Umod |
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