| No | Size | Price | Availability | |
| YRP00919-01 | 50ul | 1500.00 | In Stock |  |
| YRP00919-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6870 |
| Isotype: | IgG | Swiss Prot: | |
| purity: | Purified by Protein A. |
| Background: |
| The tachykinins belong to an evolutionary conserved family of peptide neurotransmitters that share the C-terminal sequence Phe-X-Gly-Leu-Met-NH2 and have an established role in neurotransmission. The mammalian tachykinins include substance P, neurokinin A (NKA) and neurokinin B (NKB) which exert their effects by binding to specific receptors. Tachykinin peptides are important in the mediation of many physiological and pathological processes including inflammation, pain, migraine headache and allergy induced asthma.Three tachykinin receptor types have been characterized, NK-1, NK-2 and NK-3 which have preferential affinities for SP, NKA and NKB respectively. All three receptors share a high degree of sequence homology, have seven transmembrane spanning domains and similar signal transduction mechanisms (e.g. G-protein coupled activation of phospholipase C). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic peptide derived from human TACR3 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | MGC148060, MGC148061, Neurokinin B receptor, Neuromedin K Receptor, Neuromedin-K receptor, NK 3 receptor, NK-3 receptor, NK-3R, NK3 receptor, NK3R, NK3R_HUMAN, NK 3R, NK3 receptor, NK3R, NKR, TAC 3R, TAC3R, TAC3RL, Tachykinin receptor 3, TACR 3, TACR3. |
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