| No | Size | Price | Availability | |
| YRP03434P-01 | 50ul | 1500.00 | In Stock |  |
| YRP03434P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6774 |
| Isotype: | IgG | Swiss Prot: | P40763 |
| purity: | Purified by Protein A. |
| Background: |
| Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity). |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human STAT3 around the phosphorylation site of Ser727 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | APRF, HIES, ADMIO, Signal transducer and activator of transcription 3, Acute-phase response factor, STAT3 |
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