| No | Size | Price | Availability | |
| YRP03433P-01 | 50ul | 1500.00 | In Stock |  |
| YRP03433P-01 | 100ul | 2000.00 | In Stock | |
| Source: | Rabbit | Gene Id: | 6773 |
| Isotype: | IgG | Swiss Prot: | P52630 |
| purity: | Purified by Protein A. |
| Background: |
| Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. |
| Reactivity | Human, Mouse, Rat |
| Tested applications | WB IHC IF |
| Clonality | Polyclonal Antibody |
| Calculated MW | / |
| Recommended Dilutions |
WB 1:100-1:1000
IHC 1:100-1:500
IF 1:50-1:200
|
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human Stat2 around the phosphorylation site of Tyr690 |
| Storage | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months |
| Synonym | P113, ISGF-3, STAT113, Signal transducer and activator of transcription 2, STAT2 |
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